In a small bowl, combine the salt, black pepper, garlic powder, onion, powder, Italian seasoning, and tomato paste. Mix well. Coat the roast in the mixture and place in the slow cooker. Set the onions and peppers on top of the beef and pour the beef broth over top.
Cook, on high, for 4 hours or low for 8 hours. Remove the roast and shred. Return the shredded beef to the slow cooker and mix with the peppers and broth. Serve the shredded beef on it's own, with BBQ sauce, or on a sandwich!