Potassium Intake and Strokes in Women

What is the link between potassium and stroke risk?

By Kathryn Doyle
Reuters Health

Postmenopausal women who get more potassium in their diets are less likely to have a stroke or die than those who don’t get as much, according to a new study.

Potassium-rich diets have been linked to lower blood pressure before, but this is the first time potassium has been tied to stroke risk, said senior author Sylvia Wassertheil-Smoller of the Department of Epidemiology and Population Health at Albert Einstein College of Medicine in New York.

Her team analyzed data from the Women’s Health Initiative study on 90,137 postmenopausal women, ages 50 to 79. At one and three years after enrollment, the women filled out dietary questionnaires.

Overall, they stayed in the study for an average of 11 years.

The researchers used the dietary questionnaires and potassium values for common foods to determine that the women consumed an average of 2,611 milligrams of potassium per day.

According to Food and Drug Administration labels, adolescents and adults should be consuming at least 4,700 mg of potassium daily. Bananas, avocados and other fruits and vegetables are good sources of potassium. A medium-sized banana has about 420 mg of potassium, while a cup of avocado has 708 mg.

The researchers then divided the women into four groups based on potassium consumption, from those who got less than 1,926 mg per day, the least potassium, to those who got more than 3,194 mg per day, the most.

Each year, out of every 1,000 women in the study, about three suffered a stroke and nearly 12 died of any cause.

Women who ate the most potassium were 12 percent less likely to suffer a stroke and 10 percent less likely to die during the study period than those who ate the least, according to results in Stroke.

“Potassium is a vital component of cellular function,” Wassertheil-Smoller said. “It affects endothelial cells which line blood vessels, so perhaps it may provide more blood flow to critical areas – that is one thought, but we don’t really know.”

The effect was strongest for women without high blood pressure, which was surprising, Wassertheil-Smoller told Reuters Health by email.

“This and previous observational studies cannot prove that it is potassium that lowers stroke risk,” said Susanna C. Larsson of the Institute of Environmental Medicineat Karolinska Institutet in Stockholm, Sweden.

Larsson was not involved in the new research.

“It may be other nutrients or combinations of nutrients in potassium-rich foods that are protective,” she told Reuters Health by email.

Maintaining a healthy body weight, being physically active, not smoking, and drinking alcohol in moderation reduces the risk for stroke, Larsson said.

“The reduction in stroke risk associated with a high dietary potassium intake is quite modest compared with other modifiable risk factors such as smoking,” she said.

Potassium in food may be more beneficial than potassium in supplements, Wassertheil-Smoller said.

The relationship between potassium and stroke is likely the same for men, although men tend to eat both more calories and more potassium in a day, she said.

The U.S. Department of Agriculture and the Institute of Medicine recommend 4,700 mg of potassium per day regardless of age or sex, while the World Health Organization recommends about 3500 mg per day, but most people in the U.S. don’t meet either of those goals, she said.

SOURCE: http://bit.ly/1ol13Ej Stroke, September 4, 2014

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